Can antibiotics lead to acid reflux? date: september 16, 2018 share acid reflux is a condition caused by the rushing back of food and acid from the stomach into the esophagus normally, a band of muscles known as the lower esophageal sphincter (les) contract to prevent contents of the stomach from coming back up into the esophagus. Gerd antibiotic. It was antibiotics and the gastritis i got in reaction to them that first made my doctor realize that i had gerd i have actually been hospitalized because an antibiotic causing very bad gastritis increased my reflux and created havoc with my asthma.
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